How to Soothe Vaccine Side Effects Using CBD

If you feel like you have tons of questions about getting your COVID-19 vaccine, then you aren’t alone. This is a highly popular topic right now that really affects all of us on some level. Whether you’ve already gotten your vaccine or are still thinking about scheduling that first appointment, it is important to be aware of potential side effects that can happen immediately after each dose.

Now, we definitely aren’t bringing this up to scare anyone off. However, it is widely documented that minor discomfort is possible with all three available options: Moderna, Pfizer-BioNTech, and Johnson & Johnson. Swelling, soreness, and a general feeling of illness are all quite common in the first couple of days after a dose, which indicates that the vaccine is doing what it is supposed to.

The good news? There are safe and effective ways to help minimize the pain and overall feeling of malaise with cannabidiol (CBD). As a strong anti-inflammatory, CBD is an excellent option for reducing those symptoms and ensuring your daily life isn’t affected after each dose.

Here’s what you should know about soothing COVID-19 vaccine side effects using CBD therapy.

COVID-19 Vaccine & CBD: Topical or Oral?

If you’re wondering what type to choose after your COVID-19 vaccination, the answer is both. CBD for topical use is great for soothing the injection site and reducing pain in specific areas. But the oral dose is also an excellent option for relieving all-over pain and discomfort.

That’s why we’re happy to offer our Cerena Recovery Kit. It includes both our Remedio salve for topical use and our Alivio CBD-rich oil for a mental and immune system boost. Combining the two is a great way to utilize terpenes for pain relief after your COVID-19 vaccination.

Before Your Initial Dose Appointment

About an hour before your first vaccine appointment, try taking a full dropper dose of our Alivio sublingual formula. Not only will this help prepare your body for the vaccine itself, but it can help calm any nervousness or anxiety you’re feeling about the process.

Since full-spectrum CBD products only contain 0.3% THC and won’t get you “high”, you’ll be fine to drive to your doctor’s office or wherever you’ll be rolling up your sleeve. The main benefit to starting with this protocol before that first dose is that your body will be more relaxed and receptive to the vaccine’s impact on your immune system.

After the First Appointment

Most people report that they feel absolutely fine after their first appointment. However, some individuals might need a little extra care, whether that’s due to nerves or just feeling off for a few hours post-vaccine. If this is the case, consider following up with a dose of Nocturno sublingual formula before you head to bed that night. Not only can Nocturno help you sleep through some of the vaccine side effects, it can also improve REM sleep which is the most restorative stage of our sleep cycle.

However, the real symptoms are said to include soreness at the injection site anywhere from several hours to a day or two after the dose. Some people also get a red rash or so-called ring on their skin. Those experiencing these side effects can follow with our Remedio topical balm directly on the skin. The organic CBD + CBG in this formula will soothe soreness and any muscle aches and pains you might have.

Before Your Second Appointment

When it comes time for that Moderna or Pfizer second dose, you’ll want to plan to repeat pretty much the same process as before your first appointment. Use a dropper full of the Alivio to help calm your nerves and ensure you’re feeling your best when it comes time for your final shot.

We also suggest getting enough rest the night before and ensuring you’re drinking enough water. Part of living a holistic lifestyle means treating your body well and not just masking symptoms. Thinking about hydration and sleep ahead of time is a good way to feel your best at all times – not just before your COVID-19 vaccination appointment.

After the Final Dose

As millions of people who have had their second vaccine will tell you, the side effects at this point are often the worst. You might feel as though you have chills or even run a low-grade fever. And many experience body aches similar to when you’ve gotten the flu.

The good news is that you can absolutely use CBD for sore muscles. However, in this case, we suggest pairing up a dose of our sublingual drops with a topical salve for an added boost of well-being, inside and out.

Conclusion: How to Soothe COVID-19 Vaccine Side Effects Using CBD

Now that you know how to use Cerena’s CBD-rich oils and topical salves for soothing the side effects of the COVID-19 vaccine, we would love to hear from you. If you’ve done this protocol after your first or second shot, please contact us and let us know how well it worked. 


In Spanish, "El Sereno" is a term that describes the palpable feeling in the air as the late afternoon transitions into early evening, when the heat of the day gently cools and an evening dew starts to form.